Stem Cell Treatment by Condition: What the Evidence Shows

Stem cell treatment is marketed for a very long list of conditions. The evidence behind each is wildly different, and clinics rarely distinguish between them.

This section reviews each condition separately and rates the evidence honestly.

How we rate the evidence

RatingWhat it means
EstablishedMultiple randomised controlled trials or decades of clinical practice. Standard care.
PromisingRandomised evidence exists and is encouraging, but questions remain about who benefits.
ExperimentalEarly trials or small studies only. No reliable evidence of benefit over placebo.
UnsupportedWidely marketed, but no high-quality evidence of benefit for this use.

The current picture

ConditionEvidence ratingSummary
Leukaemia, lymphoma, sickle cellEstablishedHaematopoietic transplantation is standard hospital care and FDA approved
Aggressive relapsing-remitting MSPromisingAHSCT outperformed standard therapy in randomised trials; serious hospital procedure
Knee osteoarthritisExperimentalMeta-analysis suggests most benefit is placebo-related; certainty of evidence low
Degenerative disc diseaseExperimentalSmall trials, mixed results
Peripheral neuropathyExperimentalLimited controlled evidence
COPDUnsupportedWidely sold; no high-quality randomised evidence of benefit
AutismUnsupportedNo credible evidence; heavily marketed to desperate families
Anti-ageing / longevityUnsupportedNo evidence of life extension or biological age reversal in humans
Hair lossExperimentalEarly evidence, mostly for related products rather than stem cells

A note on desperate situations

Some of the conditions above have no good treatment options, which is exactly why unproven treatments are marketed for them. If you or someone you love is in that position, we are not telling you what to decide. We are telling you what the evidence says, so the decision is at least an informed one.